Most common 2007 Mercedes-Benz E350 problems
Share of the 350 complaints; one complaint can involve more than one system. "~" is the median mileage when the problem started.
Mercedes-Benz E350 complaints by model year
Best E350 years: 2017, 2015, 2020. Years to avoid: 2014, 2011, 2012, 2013, 2006. Compare all years →
2007 Mercedes-Benz E350 recalls (5)
Visibility › Sun/moon roof assembly
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2001-2011 C-Class, CLK, E-Class, and CLS vehicles. Please see the recall report for a complete list of models and model years. The glass sunroof panel may not be properly secured and can detach.
Remedy: Dealers will inspect and replace the sunroof panel as necessary, free of charge. Owner notification letters were mailed January 10, 2025. Owners may contact MBUSA customer service at 1-800-367-6372.
Visibility › Sun/moon roof assembly
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2001-2011 C-Class, CLK, E-Class, and CLS vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The glass sunroof panel may not be properly secured and may detach.
Remedy: Dealers will inspect and replace the sunroof panel as necessary free of charge. Owner notification letters were mailed February 3, 2023. Owners may contact MBUSA customer service at 1-800-367-6372.
Visibility › Sun/moon roof assembly
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2006-2007 C350, C230, C280, CLK350, E320CDI, E350 Wagon, E350, 2006 C55 AMG, CLK500, CLS500, CLS55 AMG, E500 Wagon, E500, E55 AMG, 2007 CLK550, CLS550, CLS63 AMG, E550, E63 AMG, and E63 Wagon AMG vehicles.
Remedy: MBUSA will notify owners, and dealers will inspect the glass panel bonding and replace the sliding roof, as necessary, free of charge. Owner letters were mailed May 7, 2021.
Visibility › Sun/moon roof assembly
Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2001-2011 vehicles. The bonding between the glass panel and the sliding roof frame may deteriorate, possibly resulting in the glass panel detaching from the vehicle. For a full list of the affected models visit: https://static.nhtsa.gov/odi/rcl/2019/RMISC-19V918-4126.pdf
Remedy: MBUSA will notify owners, and dealers will inspect the glass panel bonding and replace the sliding roof, as necessary, free of charge. The recall began July 10, 2020.
Suspension › Rear
Mercedes-Benz is recalling certain model year 2007-2009 e350 4matic wagon vehicles manufactured from July 1, 2006, through April 30, 2009. A connecting rod for the load leveling rear suspension system May fail.
Remedy: Mercedes-Benz will notify owners, and dealers will replace all the connecting rods, free of charge. The safety recall began on September 7, 2012. Owners May contact Mercedes-Benz at 1-800-367-6372.
NHTSA defect investigations
Federal safety investigators have looked into a possible defect involving the 2007 Mercedes-Benz E350:
Fuel Leakage From The Fuel Tank
The Office of Defects Investigation (ODI) opened this investigation on January 23, 2012 as PE12-001 based on 20 consumer reports in model year (MY) 2003-2006 E55 AMG vehicles.Based on new reports in other E-Class vehicles, ODI upgraded the investigation to Engineering Analysis (EA) 13-003 on March 15, 2013, and expanded the scope to all E-Class vehicles through MY 2008.The complainants alleged a strong odor of…
What 2007 Mercedes-Benz E350 owners say
Fuel & propulsion system all 253 →
The contact owns a 2007 Mercedes-Benz E350. The contact stated that while refueling the vehicle, the vehicle emitted an abnormally strong gasoline odor inside and outside the vehicle. The vehicle was taken to the dealer and the contact was informed that the failure was related to an unknown NHTSA ID Number; however, the campaign had expired. The vehicle had not been repaired. The manufacturer was made aware of the failure and referred the contact to the NHTSA Hotline. The approximate failure mileage was 77,000.
The contact owns a 2007 Mercedes-Benz E350. The contact stated that the vehicle leaked gasoline into the rear driver's side seat causing a pool of gasoline under the seat. The contact stated that the check engine warning light was illuminated. The vehicle was diagnosed but not yet repaired. The manufacturer was informed of the failure. The contact was provided information of a possible manufacturer's recall. The failure mileage was approximately 104,000.
Engine & cooling all 33 →
The contact owns a 2007 Mercedes-Benz E350. The contact stated that while the vehicle was parked with the engine running, the contact heard a loud rattling sound coming from the engine compartment. The contact called an independent mechanic and was informed that the camshaft balancer was damaged and needed to be replaced. The vehicle was not repaired. The manufacturer was not made aware of the failure. The failure mileage was approximately 257,000.
Vehicle began shaking on the highway. It was coming from under the front hood and was shaking the steering wheel. The check engine light came on. I pulled over and had it towed to the Mercedes repair shop. They said it was related to a bad balance shaft and that it was a systemic problem with the engine in certain Mercedes e350s. I was told I needed to replace the camshaft and it would cost $6,000!!! After some research, it looks like Mercedes agreed, back in 2015, to cover only certain of these Mercedes, but there was no recall. I could have been killed if I was rear ended.
Transmission & drivetrain all 21 →
The contact owns a 2007 Mercedes-Benz E350. The contact stated while driving approximately 65 MPH, the check engine warning light illuminated and with an abnormal sound coming from the gear shifter. The contact stated there was a failure with the transmission and the vehicle would not exceed 65 MPH. The transmission was replaced. The contact was unable to reach the manufacturer; however, several voicemails left for the manufacturer. The approximate failure mileage was 100,000.
30 aug.16 took my 07 E350 with 29427 miles to the dealership because the check engine light came on and the car was hard starting. After arriving I informed the service writer the car had shut down while driving. We were proceeding through a busy major intersection when the car shut down. Luckily it started so we could safely exit the busy major intersection. After a diagnostic test was ran, I was informed the crankshaft hall sensor was defective. Additionally, the engine control unit, engine wiring harness, crank sensor and various other components are oil soaked. I notified Mercedes Benz to be told the car was out of warranty. Mercedes Benz should be held accountable for the unsafe defective materials they use. The above issues are a danger to the occupants and general public as well. The defective oil soaked wiring harness is can cause a fire. …
2007 Mercedes-Benz E350 engines & fuel economy
| Engine | Transmission | Drive | MPG city / hwy / combined |
|---|---|---|---|
| 3.5L 6-cyl | 7-speed automatic | RWD | 17 / 24 / 19 |
EPA ratings. Class: Midsize car.
Frequently asked questions
Is the 2007 Mercedes-Benz E350 a good car?
Based on 350 owner complaints filed with NHTSA, the 2007 E350 rates avoid: 3.5× as many complaints as a typical year of the E350 at the same age. It is one of the E350 years we suggest avoiding. Complaint counts don't account for sales volume or individual maintenance, so have any used car inspected before buying.
What is the most common problem with the 2007 Mercedes-Benz E350?
The fuel & propulsion system — 253 complaints, 72% of all complaints for this model year, most often about storage › tank assembly. Next are the engine & cooling (33) and transmission & drivetrain (21).
How many recalls does the 2007 Mercedes-Benz E350 have?
There are 5 recalls for the 2007 Mercedes-Benz E350, the most recent from November 19, 2024 (sun/moon roof assembly). Recall repairs are free at any authorized dealer — check whether yours has been done with the VIN recall check.
What are the best and worst years of the Mercedes-Benz E350?
The best years by complaints, compared at the same age, are 2017, 2015 and 2020. Years to avoid or approach with caution: 2014, 2011, 2012, 2013 and 2006. See the full Mercedes-Benz E350 years comparison.
At what mileage do 2007 Mercedes-Benz E350 problems happen?
The median mileage reported in complaints is about 76,000 miles; 23% of problems with a recorded mileage started before 50,000 miles.
Source: U.S. National Highway Traffic Safety Administration (NHTSA) — owner complaints through October 20, 2026, recalls and defect investigations; fuel economy from the EPA. Complaints are unverified reports and are not proof of a defect. How we rate model years.