Most common 2022 Mercedes-Benz E350 problems
Share of the 9 complaints; one complaint can involve more than one system. "~" is the median mileage when the problem started.
Mercedes-Benz E350 complaints by model year
Best E350 years: 2017, 2015, 2020. Years to avoid: 2014, 2011, 2012, 2013, 2006. Compare all years →
2022 Mercedes-Benz E350 recalls (3)
Fuel system, gasoline › Delivery › Fuel pump
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2024 GLE, GLS, C-Class, E-Class, S-Class, SL, GLC, CLS, AMG GT, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, causing a loss of drive power.
Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 28, 2024. Owner notification letters will be mailed in phases, on February 23, 2024, April 19, 2024, June 28, 2024,…
Fuel system, gasoline › Delivery › Fuel pump
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.
Steering › Steering wheel/handle bar
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel.
Remedy: Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372.
What 2022 Mercedes-Benz E350 owners say
Driver assistance
This vehicle on an ongoing basis is reporting false speed limits. It consistently abruptly drops the indicated speed limit from 70MPH on [redacted] northbound in Salt Lake City. the vehicle slows itself abruptly in traffic that is sometimes dense and traveling 70 to 80. An eventual rear end collision seems likely which could involve multiple vehicles. It intermittently presents the same risk in other locations with no as yet recognized associated variables such as the one location on [redacted]. Exact start and stop of the erroneous speed limit are not consistent. Sometimes brief and sometimes for a mile or more.
2022 Mercedes-Benz E350 with Driver Assistance Package. Two incidents of uncommanded automatic braking with no vehicle ahead and no debris on the road: (1) October 7, 2026, 4:30 AM - Active Brake Assist braked automatically on a clear road in dark conditions; (2) second incident of the same kind, date unknown. No collision resulted, but sudden uncommanded braking in live traffic is a serious rear-end crash risk.
2022 Mercedes-Benz E350 engines & fuel economy
| Engine | Transmission | Drive | MPG city / hwy / combined |
|---|---|---|---|
| 2.0L 4-cyl turbo | 9-speed automatic | RWD | 23 / 31 / 26 |
EPA ratings. Class: Midsize car.
Frequently asked questions
Is the 2022 Mercedes-Benz E350 a good car?
Based on 9 owner complaints filed with NHTSA, the 2022 E350 rates better than average: 40% fewer complaints than a typical year of the E350 at the same age. Complaint counts don't account for sales volume or individual maintenance, so have any used car inspected before buying.
What is the most common problem with the 2022 Mercedes-Benz E350?
The driver assistance — 3 complaints, 33% of all complaints for this model year, most often about warnings. Next are the fuel & propulsion system (1) and electrical system (1).
How many recalls does the 2022 Mercedes-Benz E350 have?
There are 3 recalls for the 2022 Mercedes-Benz E350, the most recent from December 21, 2023 (fuel pump). Recall repairs are free at any authorized dealer — check whether yours has been done with the VIN recall check.
What are the best and worst years of the Mercedes-Benz E350?
The best years by complaints, compared at the same age, are 2017, 2015 and 2020. Years to avoid or approach with caution: 2014, 2011, 2012, 2013 and 2006. See the full Mercedes-Benz E350 years comparison.
At what mileage do 2022 Mercedes-Benz E350 problems happen?
The median mileage reported in complaints is about 14,000 miles; 100% of problems with a recorded mileage started before 50,000 miles.
Source: U.S. National Highway Traffic Safety Administration (NHTSA) — owner complaints through October 20, 2026, recalls and defect investigations; fuel economy from the EPA. Complaints are unverified reports and are not proof of a defect. How we rate model years.