Most common 2021 Mercedes-Benz S580 problems
Share of the 34 complaints; one complaint can involve more than one system. "~" is the median mileage when the problem started.
Mercedes-Benz S580 complaints by model year
Best S580 years: 2024, 2023. Compare all years →
2021 Mercedes-Benz S580 recalls (16)
Service brakes, hydraulic › Foundation components
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 S 500, Maybach S 580 4MATIC, 2021-2023 S 580 4MATIC, 2022 S 680 4MATIC, and 2023 S 580e 4MATIC vehicles. The front brake hoses may rupture and leak brake fluid.
Remedy: Dealers will replace the front brake hoses, free of charge. Owner notification letters were mailed April 25, 2025. Owners may contact MBUSA customer service at 1-800-367-6372.
Communication › Auto crash notification
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 Maybach S 580 4MATIC, S 500 4MATIC, and S 580 4MATIC vehicles. The emergency call system may fail to place an automatic or manual call and may not provide the vehicle location as intended.
Remedy: Dealers will update the communication module software, free of charge. Owner notification letters were mailed December 6, 2024. Owners may contact MBUSA customer service at 1-800-367-6372.
Engine and engine cooling › Engine › Engine control module (ECU/ECM) › Software
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 S580, and Maybach S580 vehicles. In the event of a mechanical failure in the engine Camtronic system, the engine control unit (ECU) software may cause the engine to overheat or stall.
Remedy: Dealers will update the ECU software, free of charge. Owner notification letters were mailed on November 15, 2024. Owner notification letters will be mailed in phases, on November 15, 2024, January 10, 2025, and…
Fuel system, gasoline › Delivery › Fuel pump
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.
Structure › Frame and members
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 Maybach S580 and S580 vehicles. The bulkhead that separates the engine compartment from the passenger compartment may not have been properly sealed, causing water to drain into the passenger compartment.
Remedy: Dealers will repair the bulkhead front wall sealing, free of charge. Owner notification letters were mailed May 12, 2023. Owners may contact MBUSA customer service at 1-800-367-6372.
Visibility › Fixed panaramic roof/sky light assembly
Mercedes-Benz USA, LLC (MBUSA) is recalling one 2021 S 580 4Matic vehicle. The fixed front glass panel between the windshield and the panoramic sunroof may not be properly secured and may detach.
Remedy: Dealers will replace the front fixed glass panel, free of charge. The owner notification letters were mailed March 17, 2023. The owner may contact MBUSA customer service at 1-800-367-6372.
Show 10 more recalls
Back over prevention › Display function
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 AMG EQS53, EQS580, EQS450, 2021 S500, S580, and Maybach S580 vehicles. The rearview camera may not display the rearview image due to a software error in the MBUX multimedia system.
Remedy: Dealers will update the MBUX multimedia system software, free of charge. Owner notification letters are expected to be mailed August 19, 2022. Owners may contact MBUSA customer service at 1-800-367-6372.
Communication › Auto crash notification
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details.
Remedy: The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022.
Steering › Column
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 S580 4Matic and S500 4Matic vehicles. The electrical connector to the steering column module may not be secured properly, which can disable gear shifts and/or safety features including the electronic stability program, the driver's air bag, and turn signal indicators.
Remedy: Dealers will inspect and reinstall the cover for the electrical connector, as necessary, free of charge. Owner notification letters were mailed May 13, 2022. Owners may contact MBUSA customer service at 1-800-367-6372.
Steering › Steering wheel/handle bar
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel.
Remedy: Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372.
Exterior lighting › Hazard flashing warning lights
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 EQS 450, EQS 580, and 2021 S500 and S580 vehicles. A software error may disable the rear turn signals, hazard lights, and reverse lights.
Remedy: Dealers will update the rear signal software, free of charge. Owner notification letters were mailed May 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040013.
Air bags › Critical fasteners
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 S580 4Matic vehicles. The air bag control unit may be improperly secured and may result in an unintentional air bag or seat belt deployment, or an improper deployment in the event of a crash.
Remedy: Dealers will inspect and tighten the air bag control unit fastening nuts, as necessary, free of charge. Owner notification letters were mailed April 15, 2022. Owners may contact MBUSA customer service at 1-800-637-6372.
Electrical system › Software
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 S580, 2022 EQS450, EQS580, and S500 vehicles with an active and connected Mercedes me connect account. The MBUX infotainment system might allow activation of the television and internet display while driving, causing a distraction for the driver.
Remedy: MBUSA has updated their computer server to correct the issue for most vehicles, free of charge. For vehicles that were not able to be updated remotely, dealers will provide the software update, free of charge.
Engine and engine cooling › Engine › Engine control module (ECU/ECM) › Software
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 S580 and Maybach S580 vehicles. An engine control unit software error may cause a sudden engine stall, without the ability to restart the vehicle.
Remedy: Dealers will update the engine control unit software, free of charge. Owners notification letters were mailed on January 28, 2022. Owners may contact MBUSA customer service at 1-800-367-6372.
Air bags › Sensor › Occupant classification › Front passenger
Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2021 S500, S580, and Maybach S580 vehicles. The air bag control unit software may deactivate the occupant recognition control unit, resulting in a deactivated front passenger air bag.
Remedy: Dealers will update the air bag control unit software, free of charge. Owner notification letters were mailed December 1, 2021. MBUSA's number for this recall is 2021100010.
Fuel system, gasoline › Delivery › Fuel pump
Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2021 S580 vehicles. The suction jet pump in the fuel tank may have a loose or missing nozzle, which can cause the pump to fail and result in an engine stall.
Remedy: Dealers will inspect and replace as necessary, the fuel tank including the suction jet pump, free of charge. Owner letters were mailed October 26, 2021. Owners may contact MBUSA customer service at 1-800-367-6372.
What 2021 Mercedes-Benz S580 owners say
Electrical system
The contact owns a 2021 Mercedes-Benz S580. The contact received notification of NHTSA Campaign Number: 22V365000 (Electrical System, Communication) however, the parts to do the recall repair were not available. The contact stated that the manufacturer had exceeded a reasonable amount of time for the recall repair. The local dealer was notified of the issue and confirmed that parts were not available. Additionally, the contact stated that while driving or while the vehicle was idling, several warning lights and computer screen intermittently illuminated and malfunctioned. The vehicle was taken to the dealer where it was diagnosed that a system software update was needed. The vehicle was repaired; however, the failure recurred. The manufacturer was notified of the failure and the contact was informed that the part was not yet available. The failure mileage was approximately 20,000.
The contact owns a 2021 Mercedes-Benz S580. The contact stated that while driving at various speeds, the "Camera System Unavailable" and "Camera Dirty" messages were displayed on the instrument panel. The vehicle was initially taken to a dealer where the contact was informed that the failure was caused by a bumper guard placed on the front license plate, rendering the driving assist sensor inoperable. Despite the removal of the bumper guard, the failure persisted. Recently, the contact received text from the dealer that stated that several other owners of the model year vehicle had experienced the same failure. The letter stated that a defective camera lens hood had caused the failure; however, the parts for the repair were on backorder. The manufacturer was not notified of the failure. The vehicle was not repaired. The failure mileage was approximately 1,000.
Engine & cooling
The contact owns a 2021 Mercedes-Benz S580. The contact stated that while driving, the navigation system became inoperable. There were several unknown warning lights illuminated. The contact received notification of NHTSA Campaign Number: 21V843000 (Engine and Engine Cooling) however, the part to do the recall was unavailable. The vehicle was taken to the local dealer however, the mechanic was unable to duplicate the failure. The contact stated that the manufacturer exceeded a reasonable amount of time for the recall repair. The manufacturer was notified of the failure however, no further assistance was provided. VIN tool confirms parts are not available. The approximate failure mileage was 600.
The contact owns a 2021 Mercedes-Benz S 580. The contact received notification of NHTSA Campaign Number: 24V704000(Engine and Engine Cooling); however, the part to do the recall repair was not yet available. The contact stated that while starting the vehicle, the engine made an abnormal ticking sound. There was no warning light illuminated. The local dealer was contacted. The vehicle was not diagnosed or repaired. The contact stated that the manufacturer had exceeded a reasonable amount of time for the recall repair. The manufacturer was not made aware of the failure. The failure mileage was approximately 38,000. VIN tool confirms parts not available.
Wheels & tires
The contact owns a 2021 Mercedes-Benz S580 equipped with Pirelli tires, Tire Line: P Zero MO-S, Tire Size: P255/35/R21 (Front tires) and P285/30/R21 (Rear Tires), DOT Number: (Unavailable). The contact stated while driving 30 MPH, the drove over a pothole and the driver's side front tire experienced a blowout. The vehicle was towed to the dealer, and the contact was informed that there was a bubble on the side shoulder of the tire, and the tire needed to be replaced. The tire was replaced. The contact stated that a similar failure reoccurred with the front passenger's side tire and the rear driver's side tire. The vehicle was taken to the dealer both times and the contact was informed that the sidewalls on the tires were thin causing the blowouts. The failure mileage was 3,000.
I purchased this car as a certified pre-owned vehicle from Mercedes Benz in December 2024 with 14,000 miles on the odometer. This vehicle has factory 21-inch AMG rims. Since that time, I have had to replace 5 tires on this vehicle, all from Mercedes Benz dealerships. I purchased an additional $2,000 tire insurance policy from Mercedes Benz due to this recurrent issue. Due to the size of this rim, these tires are extremely prone to blowing and flats. Furthermore, this vehicle does not come with a spare tire or even with a storage compartment which can accommodate a spare tire. I was under the impression that this is because Mercedes Benz equips these vehicles with run-flat tires, however I recently learned that Mercedes does not offer run-flat tires on the 21 inch rim, leaving customers with no choice to but have the vehicle towed each time a flat tire occurs. …
Frequently asked questions
Is the 2021 Mercedes-Benz S580 a good car?
There isn't enough complaint history for the S580 to compare model years reliably. So far owners have filed 34 complaints with NHTSA.
What is the most common problem with the 2021 Mercedes-Benz S580?
The electrical system — 10 complaints, 29% of all complaints for this model year, most often about instrument cluster/panel. Next are the engine & cooling (8) and wheels & tires (8).
How many recalls does the 2021 Mercedes-Benz S580 have?
There are 16 recalls for the 2021 Mercedes-Benz S580, the most recent from February 24, 2025 (foundation components). Recall repairs are free at any authorized dealer — check whether yours has been done with the VIN recall check.
What are the best and worst years of the Mercedes-Benz S580?
The best years by complaints, compared at the same age, are 2024 and 2023. See the full Mercedes-Benz S580 years comparison.
At what mileage do 2021 Mercedes-Benz S580 problems happen?
The median mileage reported in complaints is about 3,000 miles; 100% of problems with a recorded mileage started before 50,000 miles.
Source: U.S. National Highway Traffic Safety Administration (NHTSA) — owner complaints through October 20, 2026, recalls and defect investigations; fuel economy from the EPA. Complaints are unverified reports and are not proof of a defect. How we rate model years.