Most common 2010 Mercedes-Benz R350 problems
Share of the 13 complaints; one complaint can involve more than one system. "~" is the median mileage when the problem started.
Mercedes-Benz R350 complaints by model year
Best R350 years: 2012, 2010, 2009. Years to avoid: 2006, 2007. Compare all years →
2010 Mercedes-Benz R350 recalls (3)
Service brakes, hydraulic › Power assist › Vacuum
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2006-2012 ML, GL, and R-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. Moisture may accumulate and cause corrosion in the brake booster housing unit, which can result in reduced brake performance or brake failure.
Remedy: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will remove the rubber sleeve, inspect the brake booster, and as necessary, replace the brake booster.
Service brakes, hydraulic › Power assist › Vacuum
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2006-2012 ML-Class, GL-Class, and R-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. Moisture may accumulate and cause corrosion in the brake booster housing unit, which can result in reduced brake performance or brake failure.
Remedy: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will remove the rubber sleeve, inspect the brake booster, and as necessary, replace the brake booster.
Air bags › Frontal › Driver side › Inflator module
Mercedes-Benz USA, LLC. (MBUSA) is recalling certain model year 2009-2010 ML320 BlueTec 4Matic, GL320 BlueTec 4Matic and R320 CDI 4Matic, 2011 E350 Cabriolet and E550 Cabriolet, 2009-2011 ML350, ML350 4Matic, ML550 4Matic, ML63 AMG, and C63 AMG, 2010-2011 ML450 4Matic Hybrid, E350 Coupe, E350 4Matic, E550 Coupe, E550 4Matic,…
Remedy: MBUSA will their notify owners, and Fiat Chrysler will notify the affected Chrysler owners. Dealers for the respective brands will replace the driver's frontal air bag module, free of charge.
NHTSA defect investigations
Federal safety investigators have looked into a possible defect involving the 2010 Mercedes-Benz R350:
Desiccated Air Bag Inflator Rupture
From 2000 through 2017, Takata produced millions of air bag inflators using two types of phase-stabilized ammonium nitrate ("PSAN") propellant -- propellant 2004 and propellant 2004L. After prolonged exposure to high temperature cycles and humidity, inflators using propellant 2004 can degrade, causing the propellant to burn too quickly when ignited.
What 2010 Mercedes-Benz R350 owners say
Air bags
Takata recall. I checked my VIN immediately following the announcement of the Takata recall in 2016, and found that my car is impacted by this recall. I then contacted the local Mercedes dealer to schedule the airbags replacement, but was advised that they will contact me once they receive the replacement air bags. I kept checking with them every 3 months, but received the same response. I just received a notice that Takata filed recently for chapter 11 in the us. I would like to understand file a complaint against Mercedes Benz USA for neglecting to replace the airbag in my car, and force the company to replace the air bag free of charge as part of this recall,
Takata recall we have been notified in February of 2016 and it is now November of 2016 and still no parts. We can't sell the car because I don't want to pass the problem onto another person and Mercedes won't give us a loaner so we have a potential risk. Telling us that it is a minimal risk doesn't help. This is beyond irresponsible! Can you please advise
Brakes
The contact owns a 2010 Mercedes-Benz R350. The contact stated while driving 5 MPH, the vehicle made a squishing an abnormal knocking sound. The contact stated that as the speed increased to 15-20 MPH, the issue ceased. The contact stated that upon driving for an extended period, the brake pedal became stiff. The brake warning light was illuminated. The contact later received notification of NHTSA Campaign Number: 22V315000 (Service Brakes, Hydraulic) however, the dealer declined to honor the recall repair because the original brake booster had been replaced by the previous owner. The contact stated that the manufacturer had exceeded a reasonable amount of time for the recall repair. The manufacturer was notified of the failure and informed the contact that the dealer needed to complete the recall repair. The vehicle was not repaired. The failure mileage was approximately 120,000. …
The contact owns a 2010 Mercedes-Benz R350. The contact stated that while driving at an undisclosed speed, the brake pedal was depressed and became stiff. The vehicle was taken to the dealer and diagnosed with a faulty brake booster. The vehicle was not repaired. The manufacturer was made aware of the failure. The failure mileage was approximately 130,000.
Frequently asked questions
Is the 2010 Mercedes-Benz R350 a good car?
Based on 13 owner complaints filed with NHTSA, the 2010 R350 rates better than average: 41% fewer complaints than a typical year of the R350 at the same age. It is one of the best R350 years by this measure. Complaint counts don't account for sales volume or individual maintenance, so have any used car inspected before buying.
What is the most common problem with the 2010 Mercedes-Benz R350?
The air bags — 7 complaints, 54% of all complaints for this model year. Next are the brakes (4) and engine & cooling (2).
How many recalls does the 2010 Mercedes-Benz R350 have?
There are 3 recalls for the 2010 Mercedes-Benz R350, the most recent from April 26, 2024 (vacuum). Recall repairs are free at any authorized dealer — check whether yours has been done with the VIN recall check.
What are the best and worst years of the Mercedes-Benz R350?
The best years by complaints, compared at the same age, are 2012, 2010 and 2009. Years to avoid or approach with caution: 2006 and 2007. See the full Mercedes-Benz R350 years comparison.
At what mileage do 2010 Mercedes-Benz R350 problems happen?
The median mileage reported in complaints is about 85,000 miles; 13% of problems with a recorded mileage started before 50,000 miles.
Source: U.S. National Highway Traffic Safety Administration (NHTSA) — owner complaints through October 20, 2026, recalls and defect investigations; fuel economy from the EPA. Complaints are unverified reports and are not proof of a defect. How we rate model years.