Most common 2006 Isuzu NPR problems
Share of the 9 complaints; one complaint can involve more than one system. "~" is the median mileage when the problem started.
Isuzu NPR complaints by model year
Best NPR years: 2011, 2014, 2018. Compare all years →
2006 Isuzu NPR recalls (3)
Fuel system, gasoline › Storage › Tank assembly
Isuzu Manufacturing Services of America (Isuzu) is recalling certain model year 2006-2008 Isuzu NPR and NPR-HD and Chevrolet W3500 and W4500 trucks manufactured March 16, 2005, to August 13, 2008 and 2006-2008 GMC W3500 and W4500 trucks manufactured July 18, 2005, to August 13, 2008.
Remedy: Isuzu will notify owners, and dealers will replace the fuel tank, free of charge. Isuzu issued an interim notification to owners on December 18, 2015. The recall began on April 8, 2016.
Engine and engine cooling
Isuzu is recalling certain model year 2006-2007 Isuzu npr, nqr, nrr, GMC w3500, w4500, w5500, and Chevrolet w3500, w4500, and w5500 vehicles. The oil pipe bolts were not tightened properly during the vehicle production process.
Remedy: Dealers will replace the packing seals with new ones and the bolt will be tightened with a specified torque. This service will be performed free of charge. The safety recall began on January 28, 2011.
Fuel system, diesel
Isuzu is recalling 16,859 my 2006-2007 Isuzu npr, nqr, nrr, GMC w3500, w4500, w5500 and Chevrolet w3500, w4500, w5500 trucks equipped with diesel engines. Diesel fuel May seep or leak from the fuel pipe at the upper or lower fuel port on the diesel fuel supply pump.
Remedy: Dealers will inspect the vehicles and if no seepage or leakage is detected, the fuel pipe fittings will be tightened. If seepage or leakage is detected, the fuel supply pump will be replaced with a new one.
What 2006 Isuzu NPR owners say
Suspension
While driving at highway speed, if you hit a pothole or seam in a certain way it sets in motion what we call the "death wobble" -- an uncontrollable, violent shaking of the front end that can only be stopped by slowing down dramatically (usually below 30 MPH). It feels like some sort of mechanical harmonic feedback loop is suddenly triggered in the front suspension that increases in violence and intensity as long as the vehicle continues forward. It feels like the whole truck is going to fly apart. I have had the truck into an Isuzu dealership multiple times to have this addressed with no permanent fix. The problem can be masked with new tires but it returns, well before the tires have reached what should be the end of their life. If you google "Isuzu death wobble" you will find that this is a commonly observed problem with no known solution. …
The front cab of the truck starts shaking like a tire fell off. I had the truck to the dealership a few times and have changed the tires and other front end parts, I've changed every part that the dealer told me to change and I'm still having the problem. I started looking the problem up online and found that this is a common problem that people are having and they don't know what to do to fix it.
Steering
While driving at highway speed, if you hit a pothole or seam in a certain way it sets in motion what we call the "death wobble" -- an uncontrollable, violent shaking of the front end that can only be stopped by slowing down dramatically (usually below 30 MPH). It feels like some sort of mechanical harmonic feedback loop is suddenly triggered in the front suspension that increases in violence and intensity as long as the vehicle continues forward. It feels like the whole truck is going to fly apart. I have had the truck into an Isuzu dealership multiple times to have this addressed with no permanent fix. The problem can be masked with new tires but it returns, well before the tires have reached what should be the end of their life. If you google "Isuzu death wobble" you will find that this is a commonly observed problem with no known solution. …
The front cab of the truck starts shaking like a tire fell off. I had the truck to the dealership a few times and have changed the tires and other front end parts, I've changed every part that the dealer told me to change and I'm still having the problem. I started looking the problem up online and found that this is a common problem that people are having and they don't know what to do to fix it.
Frequently asked questions
Is the 2006 Isuzu NPR a good car?
Based on 9 owner complaints filed with NHTSA, the 2006 NPR rates few complaints: 1.7× as many complaints as a typical year of the NPR at the same age. Complaint counts don't account for sales volume or individual maintenance, so have any used car inspected before buying.
What is the most common problem with the 2006 Isuzu NPR?
The suspension — 4 complaints, 44% of all complaints for this model year. Next are the steering (4) and wheels & tires (2).
How many recalls does the 2006 Isuzu NPR have?
There are 3 recalls for the 2006 Isuzu NPR, the most recent from October 26, 2015 (tank assembly). Recall repairs are free at any authorized dealer — check whether yours has been done with the VIN recall check.
What are the best and worst years of the Isuzu NPR?
The best years by complaints, compared at the same age, are 2011, 2014 and 2018. See the full Isuzu NPR years comparison.
At what mileage do 2006 Isuzu NPR problems happen?
The median mileage reported in complaints is about 133,000 miles; 25% of problems with a recorded mileage started before 50,000 miles.
Source: U.S. National Highway Traffic Safety Administration (NHTSA) — owner complaints through October 20, 2026, recalls and defect investigations; fuel economy from the EPA. Complaints are unverified reports and are not proof of a defect. How we rate model years.