Most common 2022 Mercedes-Benz S500 problems
Share of the 21 complaints; one complaint can involve more than one system. "~" is the median mileage when the problem started.
Mercedes-Benz S500 complaints by model year
Best S500 years: 2021, 2023. Years to avoid: 2022, 2000, 2001. Compare all years →
2022 Mercedes-Benz S500 recalls (9)
Service brakes, hydraulic › Foundation components
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022-2025 S 500 4MATIC, Maybach S 580 4MATIC, Maybach S 680 4MATIC, S 580 4MATIC, 2023-2025 S 580 E 4MATIC, and 2024-2025 AMG S 63 E Performance vehicles. The front brake hoses may rupture and leak brake fluid.
Remedy: Dealers will replace the front brake hoses, free of charge. Owner notification letters are expected to be mailed November 27, 2026. Owners may contact MBUSA customer service at 1-800-367-6372.
Service brakes, hydraulic › Foundation components
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 S 500, Maybach S 580 4MATIC, 2021-2023 S 580 4MATIC, 2022 S 680 4MATIC, and 2023 S 580e 4MATIC vehicles. The front brake hoses may rupture and leak brake fluid.
Remedy: Dealers will replace the front brake hoses, free of charge. Owner notification letters were mailed April 25, 2025. Owners may contact MBUSA customer service at 1-800-367-6372.
Fuel system, gasoline › Delivery › Fuel pump
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2024 GLE, GLS, C-Class, E-Class, S-Class, SL, GLC, CLS, AMG GT, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, causing a loss of drive power.
Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 28, 2024. Owner notification letters will be mailed in phases, on February 23, 2024, April 19, 2024, June 28, 2024,…
Fuel system, gasoline › Delivery › Fuel pump
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.
Structure › Interior panels › Dashboard
Mercedes-Benz USA, LLC (MBUSA) is recalling one 2022 S 500 vehicle. The dashboard may be insufficiently attached, which can result in an improper front passenger air bag deployment in the event of a crash.
Remedy: Dealers will replace a portion of the dashboard, free of charge. The owner notification letter was mailed January 20, 2023. Owners may contact MBUSA customer service at 1-800-367-6372.
Suspension › Subframe/mounting bracket
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 S580Z, S500V, and S580V vehicles. The sub frame weld for the thrust arm on the rear axle carrier may have been improperly welded, causing the thrust arm to break and detach.
Remedy: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will inspect the sub frame weld on the rear axle carrier and replace the rear axle carrier as necessary, free of charge.
Show 3 more recalls
Steering › Steering wheel/handle bar
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel.
Remedy: Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372.
Communication › Auto crash notification
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 EQS450, S500, and S580 vehicles. The communication module software may restrict or disable the emergency call system (eCall).
Remedy: The communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed February 23, 2022.
Electrical system › Software
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 S580, 2022 EQS450, EQS580, and S500 vehicles with an active and connected Mercedes me connect account. The MBUX infotainment system might allow activation of the television and internet display while driving, causing a distraction for the driver.
Remedy: MBUSA has updated their computer server to correct the issue for most vehicles, free of charge. For vehicles that were not able to be updated remotely, dealers will provide the software update, free of charge.
What 2022 Mercedes-Benz S500 owners say
Driver assistance
The contact owns a 2022 Mercedes-Benz S500. The contact stated while driving at an undisclosed speed and making a left turn, the Adaptive Braking System inadvertently activated and the vehicle experienced hard braking. There were no objects in the roadway. There were no warning lights illuminated. The contact called the local dealer who scheduled a service appointment however, the vehicle was not diagnosed or repaired. The manufacturer was contacted but no additional assistance was provided. The failure mileage was approximately 4,800. The VIN was not available.
I leased my 2022 S 500, Mercedes Benz. on September 28, 2022 and after about a year, I have had issues with the large screen/radio and cruise control in the vehicle. All events are documented at the Rockville Centre, Long Island service center. I have made numerous complaints beginning in January of this year through emails and was assigned a case number with Mercedes Benz corporate which is 12240831. On numerous occasions, while using the cruise control set to 50 MPH, the vehicle will accelerate to 80 MPH on a highway with a 50 MPH speed limit. Then on other occasions, while using the cruise control, the vehicle will accelerate to 80 MPH on a highway with a 25 MPH speed limit. Then, at other times, while using the cruise control set to 50 MPH, on a highway which has a 50 MPH speed limit, the car will reduce to 10 MPH . All of these scenarios are VERY DANGEROUS as you can well imagine. …
Electrical system
The contact owns a 2022 Mercedes-Benz S500. The contact received a notification for NHTSA Campaign Number: 21V00J000 (Electrical System, Communication) however, the parts for the repair were unavailable. The dealer had been notified about the recall and confirmed that parts were not yet available. The manufacturer had been notified of the recall. The contact stated that the manufacturer had exceeded a reasonable amount of time for the repair. The contact also mentioned that he experienced a blowout failure with the passenger's side front Pirelli PZero Tire, Tire Size: 255/35/R21, DOT Number: 1UN13874K. The contact stated that he replaced the tire with the spare; however, the vehicle was not taken to an independent mechanic or dealer. The contact stated that approximately a week later, the driver's side tire experienced the same blowout failure and was taken to an independent mechanic. …
I leased my 2022 S 500, Mercedes Benz. on September 28, 2022 and after about a year, I have had issues with the large screen/radio and cruise control in the vehicle. All events are documented at the Rockville Centre, Long Island service center. I have made numerous complaints beginning in January of this year through emails and was assigned a case number with Mercedes Benz corporate which is 12240831. On numerous occasions, while using the cruise control set to 50 MPH, the vehicle will accelerate to 80 MPH on a highway with a 50 MPH speed limit. Then on other occasions, while using the cruise control, the vehicle will accelerate to 80 MPH on a highway with a 25 MPH speed limit. Then, at other times, while using the cruise control set to 50 MPH, on a highway which has a 50 MPH speed limit, the car will reduce to 10 MPH . All of these scenarios are VERY DANGEROUS as you can well imagine. …
Wheels & tires
The contact owns a 2022 Mercedes-Benz S500. The contact received a notification for NHTSA Campaign Number: 21V00J000 (Electrical System, Communication) however, the parts for the repair were unavailable. The dealer had been notified about the recall and confirmed that parts were not yet available. The manufacturer had been notified of the recall. The contact stated that the manufacturer had exceeded a reasonable amount of time for the repair. The contact also mentioned that he experienced a blowout failure with the passenger's side front Pirelli PZero Tire, Tire Size: 255/35/R21, DOT Number: 1UN13874K. The contact stated that he replaced the tire with the spare; however, the vehicle was not taken to an independent mechanic or dealer. The contact stated that approximately a week later, the driver's side tire experienced the same blowout failure and was taken to an independent mechanic. …
I have the 2022 S 500 with 21 inch mag spoke rims with Pirelli 255/35R21 tires on it which comes stock from Mercedes Benz. I have now been in almost 15 tires repair claims and 3 rim replacements because of how poorly Mercedes designed the rims then put a tire soon the car that cannot handle the weight of the car. I hit a pot hole and my whole tire blew out almost causing a severe crash. this is again the almost 15th time this has happened. I took the car to Mercedes Beverly Hills and the service advisors say that now there is $16,000 dollars in damages on the car fro the constant impact it has taken from the rims being poorly designed on the car. I have asked many times to replace the tire brand to a better and thicker tire. but Mercedes will not allow that and demands I pay over 16k in damages to fix suspensions and the drive unit issues.
Frequently asked questions
Is the 2022 Mercedes-Benz S500 a good car?
Based on 21 owner complaints filed with NHTSA, the 2022 S500 rates use caution: 5.3× as many complaints as a typical year of the S500 at the same age. It is one of the S500 years we suggest avoiding. Complaint counts don't account for sales volume or individual maintenance, so have any used car inspected before buying.
What is the most common problem with the 2022 Mercedes-Benz S500?
The driver assistance — 9 complaints, 43% of all complaints for this model year, most often about adaptive cruise control. Next are the electrical system (6) and wheels & tires (3).
How many recalls does the 2022 Mercedes-Benz S500 have?
There are 9 recalls for the 2022 Mercedes-Benz S500, the most recent from October 2, 2026 (foundation components). Recall repairs are free at any authorized dealer — check whether yours has been done with the VIN recall check.
What are the best and worst years of the Mercedes-Benz S500?
The best years by complaints, compared at the same age, are 2021 and 2023. Years to avoid or approach with caution: 2022, 2000 and 2001. See the full Mercedes-Benz S500 years comparison.
At what mileage do 2022 Mercedes-Benz S500 problems happen?
The median mileage reported in complaints is about 5,000 miles; 100% of problems with a recorded mileage started before 50,000 miles.
Source: U.S. National Highway Traffic Safety Administration (NHTSA) — owner complaints through October 20, 2026, recalls and defect investigations; fuel economy from the EPA. Complaints are unverified reports and are not proof of a defect. How we rate model years.