Most common 2006 Ford F-450 SD problems
Share of the 35 complaints; one complaint can involve more than one system. "~" is the median mileage when the problem started.
Ford F-450 SD complaints by model year
Best F-450 SD years: 2018, 2020, 2014. Years to avoid: 2022, 2021, 2008, 1999, 2000. Compare all years →
2006 Ford F-450 SD recalls (1)
Exterior lighting › Brake lights
Ford is recalling certain model year 2011 ranger trucks built from January 25, 2011, through April 25, 2011 at the twin cities assembly plant, and service parts distributed to dealers for certain 2004 through 2011 model year ranger trucks, 2002 through 2005 model year excursion vehicles, and 2002 through 2007 model year f-250,…
Remedy: Dealers will replace the switches free of charge. The safety recall began on August 15, 2011. Owners May contact Ford motor company customer relationship center at 1-866-436-7332.
What 2006 Ford F-450 SD owners say
Fuel & propulsion system all 26 →
"delamination of fuel tank" after only having the vehicle for shortly over four months, the truck would not crank. The truck was parked on a city street in washington, dc where I racked up 2 parking tickets. I had it towed to the dealer and they said that the tank is corroding. I've had issues with the truck since I purchased it. The gas gauge would go out periodically along with the power. I called the dealer and had it checked out, and they said they couldn't find any issues. Now that the 90 day warranty is over, the goes out completely in 120 days. It took the dealer a month to deliver the truck to me after I purchased it.
Tl* the contact owns a 2006 Ford f-450 SD. The contact stated that the inner lining of the fuel tank would flake causing the fuel system to become clogged. As a result, the vehicle would lose power while driving. The failure recurred numerous times. The vehicle was taken to an independent mechanic, where it was diagnosed that the injectors and front fuel tank had to be replaced. The vehicle was repaired. The manufacturer was made aware of the failure. The failure mileage was 156,000.
Engine & cooling
This 2006 Ford e450 super duty with a 6.0l engine has been trouble right from the start. The first thing to go wrong was the turbo that went out on 09/18/2007 with only 12,000 miles. Next at 15,000 miles the vehicle had starting and running problems and the dealer replaced several parts on top of motor. From this time forward up to 29000 miles the squad was towed several times for more engine repairs and replacement parts. From 29,000 to 53,000 things got worse. The vehicle was towed in again for EGR cooler problems, injector problem and radiator failed. Two of these times was when we had a patient and had to call for a back up unit to respond. From 53,000 miles to 62,000 miles we had several more times of no start and no power problem that left the squad only able to go 35 MPH. We had more engine parts replaced and computers. …
Tl contact owns a 2006 Ford f450 . While driving at various speeds the vehicle would constantly smoke, run hot and lose power . The vehicle was then taken to the dealer who stated that this was a known failure and that the EGR oil cooler needed to be replaced. The EGR was replaced twice. The vehicle was in the dealers possession for 2 weeks for diagnostic testing. The contact will not have the vehicle repaired at the dealer since he believes that the part was defective. The vehicle was not repaired. The vehicle identification number was not available. The failure mileage was 60000 and the current mileage was 102000.
Electrical system
This 2006 Ford e450 super duty with a 6.0l engine has been trouble right from the start. The first thing to go wrong was the turbo that went out on 09/18/2007 with only 12,000 miles. Next at 15,000 miles the vehicle had starting and running problems and the dealer replaced several parts on top of motor. From this time forward up to 29000 miles the squad was towed several times for more engine repairs and replacement parts. From 29,000 to 53,000 things got worse. The vehicle was towed in again for EGR cooler problems, injector problem and radiator failed. Two of these times was when we had a patient and had to call for a back up unit to respond. From 53,000 miles to 62,000 miles we had several more times of no start and no power problem that left the squad only able to go 35 MPH. We had more engine parts replaced and computers. …
Letter from congressman noem on behalf of constituent re his difficulties with the warranty on his 2007 winnebago motor home (dot/I# h 2012 242 ) 2006 Ford 4-450 SD chassis. The consumer stated he purchased the motorhome in April of 2008. The warranty started in 2008 as it was a model year carry over unit. The warranty is set to expire in April 2013. The consumer stated the ignition coils were bad. On several occasions, through correspondence and phone calls, he requested the Ford replace the ignition coils. Six out of ten coils have failed. So far, Ford has refused.
Frequently asked questions
Is the 2006 Ford F-450 SD a good car?
Based on 35 owner complaints filed with NHTSA, the 2006 F-450 SD rates avoid: 6.4× as many complaints as a typical year of the F-450 SD at the same age. It is one of the F-450 SD years we suggest avoiding. Complaint counts don't account for sales volume or individual maintenance, so have any used car inspected before buying.
What is the most common problem with the 2006 Ford F-450 SD?
The fuel & propulsion system — 26 complaints, 74% of all complaints for this model year, most often about fuel injection system. Next are the engine & cooling (10) and electrical system (3).
How many recalls does the 2006 Ford F-450 SD have?
There is 1 recall for the 2006 Ford F-450 SD, the most recent from July 13, 2011 (brake lights). Recall repairs are free at any authorized dealer — check whether yours has been done with the VIN recall check.
What are the best and worst years of the Ford F-450 SD?
The best years by complaints, compared at the same age, are 2018, 2020 and 2014. Years to avoid or approach with caution: 2022, 2021, 2008, 1999 and 2000. See the full Ford F-450 SD years comparison.
At what mileage do 2006 Ford F-450 SD problems happen?
The median mileage reported in complaints is about 50,000 miles; 52% of problems with a recorded mileage started before 50,000 miles.
Source: U.S. National Highway Traffic Safety Administration (NHTSA) — owner complaints through October 20, 2026, recalls and defect investigations; fuel economy from the EPA. Complaints are unverified reports and are not proof of a defect. How we rate model years.